Marco Tafani, Maura Di Vito, Alessandro Frati et al., Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma. J Neuroinflammation. 2011; 8: 32.
Adaptation to hypoxia and consequent pro-inflammatory gene expression of prostate and breast carcinomas have been implicated in the progression toward cancer malignant phenotype. Only partial data are available for the human tumor glioblastoma multiforme (GBM). The aim of our study was to analyze the hypoxic and pro-inflammatory microenvironment in GBMs and to demonstrate that in a stem/progenitor cell line derived from human glioblastoma (GBM-SCs), hypoxia activates a coordinated inflammatory response, evidencing an invasive and migratory phenotype.
Mondello F, , Di Vito M, Campagna P, Scafuri A, Bouzari H, Fedele G., Strategies for the control of skin infections by drug resistant bacteria with natural products. Ordinary Project ISS 2013. Biological collaborator coordinator UNIT 2-microbiological,molecular, immunological studies on collected samples.