Andrea Muratore MD, Daria Zorzi MD, Hedayat Bouzari MD, Marco Amisano MD et al., Asymptomatic Colorectal Cancer with Un-Resectable Liver Metastases: Immediate Colorectal Resection or Up-Front Systemic Chemotherapy? Annals of Surgical Oncology February 2007, Volume 14, Issue 2, pp 766-770

From January 2000 to December 2004, we prospectively collected data on 35 consecutive patients who were treated straightaway by chemotherapy without primary tumor resection. All patients underwent FOLFOX6 as first-line chemotherapy. The aim of the study was to evaluate the rate of surgical complications related to un-resected colorectal tumor. The rate of complications related to the non-resected colorectal tumor is very low using oxaliplatin as first line chemotherapy. Non-operative management of asymptomatic colorectal cancers with un-resectable liver metastases is a safe approach.


Mondello F, , Di Vito M, Campagna P, Scafuri A, Fedele G., Strategies for the control of skin infections by drug resistant bacteria with natural products. Ordinary Project ISS 2013.  Medical Collaborator Ospedale Mauriziano TO.